Nick,
WELCOME TO THE AWS WELDING FORUM!!
Now, to accurately respond I should probably get your applicable code, process, and other essential variables in most any application.
But, I don't recall 4130 being in D1.1 so am ASSUMING you are not dealing with it.
Next, I don't recall yield strength being an essential variable and is often quite different in materials in the same class range for WPS's.
So, off the top of my head I would venture that the odds are both could be covered in one WPS but that is not a foregone conclusion based upon all the needed facts.
He Is In Control, Have a Great Day, Brent