Joaquin, can you define a little bit more what it is your welding? i.e., stainless steel, carbon steel, etc., material shapes, welding process, thickness, etc? Sequencing can definately help but we have to know some more information before we can give you any suggestions. :)
This can be a very complex subject, but the short answer is "yes". Distortion is influenced by preheat, joint restraint, heat input (bead size), prestraining or prepositioning of pieces to accomodate weld shrinkage, weld groove design (vee versus "U", single side versus double sided, etc.) welding sequence (backstepping, skip welding etc.), peening etc. The AWS Welding Handbook has a lot of information on distortion, residual stress, as does the ASM Metal Handbook volume on welding.