A very "general" rule of thumb is set the gap same size as filler. Be careful though, put good tacks in and feather them nicely as your gap will want to close up on you as you come around to the opposite side. Leave your purge going until you have a MINIMUM of two layers, or even better, 3 layers.
What process? I'm thinking TIG & if so, that's up to you as far as the scope of parameters & procedures allow. Will this be a code quality job? Will it get UT or Radiograph tested? If so, you are going to want to be very sure you're root goes in with adequate penetration & face reinforcement on the ID side of the pipe without excessive carbide precipitation. This happens when the weld gets too hot & carbon is drawn out of the structure of the metal, forming on the surface of the weld, causing eventual weakness & lack of corrosion resistance. Some put a 1/8" land & gap on their pipe, others run a smaller gap with a little less land. I would say 3/32" would be as small as you want to go on a root gap. It's probably going to close up after you get it tacked & start welding. Every pipe I ever did in school did, in one way or another. The last thing you want is a reduced root gap, or have problems with suck in if it's too big.
The gap & land size will vary from weldor to weldor, or may be specifically spelled out by a particular process cert. in which case, you will need to follow to the letter if you don't want the weld rejected by QC when they inspect it & or watch you put that root in. You will also NEED to purge the inside of the pipe with argon, or whatever shielding gas the process requires. You will have a big mess on your hands if not. Like I said, I'm not a pipe guy, but got the basics in school. I'm going off very basic instruction, nothing more. I'm sure others will add to this who are much more experienced in this field. S.W.